I haven't tried to harvest it my self, but it should be some heavy stuff to put through.
In my area we got some fairly damp conditions and the hemp is ready for harvest pretty late in the season, which doesn't help.
I dont think you need to change setup, yeah well it depends on your current setup.
I think that the draper would help you feed it....
u need really good sharp new guards and sickles and getting chaff through combine is an issue also wrapping but other than that thrashing it is not bad i think you set it simluar to wheat but open the concave a little more cant remember its been almost a year since we combined the stuff for a guy